As a PDE5 inhibitor, Tadalafil enhances blood flow to the penile area, helping achieve and sustain a firm erection when sexually stimulated. Known as the "weekend pill," its effects can last up to 36 hours.Dapoxetine (60 mg): Dapoxetine, an SSRI (selective serotonin reuptake inhibitor), acts on neurotransmitters in the brain to increase control over ejaculation, helping to delay it by 2–3 times the typical duration.